Patient Information


Diabetic foot ulcers are serious wounds and need special care. It can be frustrating to have a diabetic foot ulcer. This page will provide you with information about Omnigraft Dermal Regeneration Matrix.

Omnigraft is a two layered skin repair product. It is designed to help heal chronic diabetic foot ulcers. The bottom layer is made of bovine collagen and chondroitin. The top layer is a thin silicone layer. Omnigraft is processed and sterilized so that is can be used in humans.

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Omnigraft was evaluated in a clinical study involving adults with neuropathic diabetic foot ulcers that persisted for over 6 weeks. The study compared 154 patients treated with Omnigraft along with standard wound care (cleaning the wound, covering the wound, keeping weight off the wound) to 153 patients treated with standard wound care alone. The results of the study show that patients treated with Omnigraft experienced a greater chance of healing: 51% of patients treated with Omnigraft had healed ulcers compared to 32% of patients treated with standard wound care alone. 57 of 92 patients (62%) who received only a single Omnigraft application experienced healing of their wound. On average, ulcers treated with Omnigraft healed 5 weeks faster than ulcers treated with standard wound care alone.

What is Omnigraft?

Omnigraft is a two-layered skin repair product. It is designed to help heal chronic diabetic foot ulcers. The bottom layer is made of bovine (cow) collagen and chondroitin. The top layer is a thin silicone layer. Omnigraft is processed and sterilized so that it can be used in humans.

What is Omnigraft used for?

Omnigraft is indicated for use in the treatment of partial and full-thickness diabetic foot ulcers that are greater than six weeks in duration. Omnigraft should be used along with standard diabetic wound care (cleaning the wound, covering the wound, and keeping weight off the wound).

Who should NOT use Omnigraft?

Do not use Omnigraft if:

What warnings should I know about?

What are the possible side effects?

The most common health problems (adverse events) experienced by patients treated with Omnigraft were:

These adverse events occurred in a similar or lower percentage of patients treated with Omnigraft compared to patients treated with standard wound care alone. The risk information provided here is not comprehensive. To learn more, talk about Omnigraft with your health care provider. The FDA-approved product labeling can be found at www.omnigraft.com.